LIPOTEICHOIC ACID FUNDAMENTALS EXPLAINED

Small concentrations of S1P are chemotactic for osteoclast precursors, although higher concentrations inhibit their motion 79. This suggests that these precursors, which Specific both S1PR1 and S1PR2, are retained in the vicinity in the bone from the S1P gradient: S1PR2 stops S1PR1-induced migration of such bone-resorbing cells away from bone. S1PR